Te Whatu Ora - Nelson Marlborough, New Zealand

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Phases I & II diagnostic accuracy clinical trials were started in 2014 , at Nelson Marlborough Health. Here we tested the screening/diagnostic value of our technology. The initial trials included cohorts of “ADHD combined presentation” and “typically developing” children (5 to 13-years old). 

We recruited participants at the primary paediatrics service from Nelson Marlborough Health. The diagnostic reference standard comprised of case history, physical and neurological examinations, Conners 3rd Edition, and DSM-V.

Our technology is a computer based game inspired by 'Battleships'. Participants played the game eight times. From the game output, we computed mathematical complexity measures to be used in several machine learning, supervised classification models. 

We are currently undertaking a second clinical trial that is an extension of our first diagnostic accuracy study. We are recruiting participants that meet the following criteria and are from Nelson Marlborough :  

• Children aged 5–13 years who have autism spectrum disorder (ASD) level 1 and 2 with no comorbidities.  
• Children aged 5-13 years. This a “clinical control” cohort composed of patients referred to the paediatric department with a neurodiverse/mental health condition that excludes “ADHD combined presentation” and/or ADS level 1 and 2. 

This clinical trial is funded by HRC : https://www.hrc.govt.nz/resources/research-repository/predictive-modelling-executive-function-patterns-child

Dr Hakan Öğütlü and his research team at Ankara City hospital in Turkey are currently undertaking replication trials using the Noologica technology. Their clinical cohorts includes participants with ADHD (three presentations) and other comorbidities.

The second research site in Turkey is located in the Adolescent Psychiatry Clinic in Ankara. This replication trial is lead by Assoc. Prof. Dr Hakan Öğütlü. Collaborators include Clinical Psychologist Nalan Bingöl, Psychologist Buse Çam, and Psychologist Simay Çepni.

In the Photo (From left)  is Psy Nalan Bingöl, in the center Dr Hakan Öğütlüin and on the right Psy Buse Çam and Psy Simay Çepni.